Dr. Neil Melendez, Dr. Morgan Reznick and Dr. Claire Brown grapple with a patient’s wish to perform an operation that would keep him from acting on his pedophilic urges; and…

Dr. Shaun Murphy, Dr. Audrey Lim and Dr. Claire Brown’s E.R. patient is forced to reveal a secret to her husband after their treatment caused a complication. Meanwhile, Dr. Neil…

The brothers prepare to fight the forces of the apocalypse in different camps. While Sam and Ruby hunt down Lilith, Dean joins Castiel and Zachariah to take on Lucifer.

Dean and Bobby have something frightening locked in Bobby’s panic room: Sam, contaminated by demon blood. But as the apocalypse draws nearer, Bobby wants to free Sam to battle on…